| Projecttitle | Bioavailability and bioaccumulation of very hydrophobic organic chemicals (vHOCs) |
|---|---|
| Investigators | S.A. van der Heijden, MSc |
| Type of project | PhD project |
| Project leader | Dr. ir. M.T.O. Jonker |
| Co-operation | Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland |
| Time frame | January 2007 - January 2010 |
| Funded by |
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| Short description | |
| Aim |
To better understand bioaccumulation of vHOCs and to develop chemical methods for predicting bioavailability/bioaccumulation potential of these chemicals. |
| Methods |
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| Details |
Based on their hydrophobicity, vHOCs are expected to accumulate in animal lipids. Hence, quantification of the chemicals' bioaccumulation potential is required for environmental risk assessment. However, the determination of bioaccumulation factors for vHOCs is problematic and prone to experimental artifacts, due to limited maximum test durations and/or phase separation issues. In this project we investigate the feasibility of alternative methods for the prediction of actual vHOC bioaccumulation, as well as several mechanistic aspects of the process (dependence on hydrophobicity, temperature, and lipid composition). Experiments are performed both in the lab and in the field. |
| Related projects |
Improving risk assessment of petroleum hydrocarbon-contaminated sediments and soils (Barry Muijs). |
